lightniing Projects Teams About

NeuroImaging Infrastructure

lightniing
NeuroImaging Infrastructure: next generation.

High-performance neuroimaging built for open science—designed to run anywhere and empower everyone.

Current projects

Proven methods,
made lighter.

We credit the original creators, preserve the scientific lineage, and focus our work on deployment and performance.

RegistrationRealignment3dvolreg3dAllineate

Spatial Processing

Fast, portable voxel-based image registration for normalization and motion correction.

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Slice TimingDetrending3dTshift

Temporal Processing

High-performance voxel-based motion correction and detrending.

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Multi-echoMEDICROMEO

Spatial Unwarping

Echo planar images are inherently spatially distorted. However, phase images can be used to correct the shape of multi-echo BOLD fMRI data.

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mindgrabbrainchopAI

Brain Extraction

Accurate removal of scalp signals improves image processing. The AI-based mindgrab is a fast but robust method that works with any modality.

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WebGPUMetalstreamlines

Diffusion Imaging

Our team has accelerated popular tools for processing diffusion imaging to improve tractography.

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WebAssemblyWebGPUPrivate by design

Web Apps

Browser-native neuroimaging applications that keep data local while putting capable workflows within reach.

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Already in the field

Portable components,
practical science.

Modular building blocks that bring established neuroimaging capabilities to more people, platforms, and workflows.

niimath Compact, high-performance image maths with broad NIfTI support. dcm2niix The widely used converter from DICOM to NIfTI and BIDS sidecars. NiiVue Fast, dependency-light neuroimaging visualization for the web. mindgrab Lightweight brain extraction for practical imaging workflows. ITK-Wasm Web-ready ITK tools for high-performance medical image processing. Neurodesk Reproducible neuroimaging tools, ready across local, cloud, and HPC environments. VesselBoost Deep-learning vessel segmentation for high-resolution MR angiography. QSMxT A fast, BIDS-native pipeline for quantitative susceptibility mapping. ROMEO Fast 3D and 4D phase unwrapping for MR data. OSF project Open project materials and resources for the neuroimaging community. BIDSvue Desktop curation, de-identification, validation, and sharing for BIDS. GPUStreamlines GPU-accelerated streamline generation across CUDA, Metal, and WebGPU.